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Expression of GATA-1 in a Non-Hematopoietic Cell Line Induces β-Globin Locus Control Region Chromatin Structure Remodeling and an Erythroid Pattern of Gene Expression

GATA-1 is a hematopoietic transcription factor expressed in erythroid, megakaryocytic, mast cell and eosinophil lineages. It is required for normal erythroid differentiation, the expression of erythroid-specific genes and for the establishment of an active chromatin structure throughout the β-globin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Layon, Michael E., Ackley, Catherine J., West, Rachel J., Lowrey, Christopher H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1839823/
https://ncbi.nlm.nih.gov/pubmed/17196618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.11.094
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