Conserved elements containing NF-E2 and tandem GATA binding sites are required for erythroid-specific chromatin structure reorganization within the human beta-globin locus control region.

Proper expression of the genes of the human beta-globin gene locus requires the associated locus control region (LCR). Structurally, the LCR is defined by the presence of four domains of erythroid-specific chromatin structure. These domains, which have been characterized as DNase I hypersensitive si...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Pomerantz, O, Goodwin, A J, Joyce, T, Lowrey, C H
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1998
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC148032/
https://ncbi.nlm.nih.gov/pubmed/9838000
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