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General and Specific Functions of Exonic Splicing Silencers in Splicing Control

Correct splice site recognition is critical in pre-mRNA splicing. We find that almost all of a diverse panel of exonic splicing silencer (ESS) elements alter splice site choice when placed between competing sites, consistently inhibiting use of intron-proximal 5′ and 3′ splice sites. Supporting a ge...

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Main Authors: Wang, Zefeng, Xiao, Xinshu, Van Nostrand, Eric, Burge, Christopher B.
格式: Artigo
語言:Inglês
出版: 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1839040/
https://ncbi.nlm.nih.gov/pubmed/16797197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.05.018
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