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Recognition of Unknown Conserved Alternatively Spliced Exons

The split structure of most mammalian protein-coding genes allows for the potential to produce multiple different mRNA and protein isoforms from a single gene locus through the process of alternative splicing (AS). We propose a computational approach called UNCOVER based on a pair hidden Markov mode...

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Autori principali: Ohler, Uwe, Shomron, Noam, Burge, Christopher B
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1185642/
https://ncbi.nlm.nih.gov/pubmed/16110330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0010015
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