Inhibition of TGF-β with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression

We investigated whether TGF-β induced by anticancer therapies accelerates tumor progression. Using the MMTV/PyVmT transgenic model of metastatic breast cancer, we show that administration of ionizing radiation or doxorubicin caused increased circulating levels of TGF-β1 as well as increased circulat...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Biswas, Swati, Guix, Marta, Rinehart, Cammie, Dugger, Teresa C., Chytil, Anna, Moses, Harold L., Freeman, Michael L., Arteaga, Carlos L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838926/
https://ncbi.nlm.nih.gov/pubmed/17415413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30740
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados