Human and mouse homologs of Escherichia coli DinB (DNA polymerase IV), members of the UmuC/DinB superfamily

To understand the mechanisms underlying mutagenesis in eukaryotes better, we have cloned mouse and human homologs of the Escherichia coli dinB gene. E. coli dinB encodes DNA polymerase IV and greatly increases spontaneous mutations when overexpressed. The mouse and human DinB1 amino acid sequences s...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Gerlach, Valerie L., Aravind, L., Gotway, Garrett, Schultz, Roger A., Koonin, Eugene V., Friedberg, Errol C.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1999
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18388/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10518552/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.21.11922
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!