Human and mouse homologs of Escherichia coli DinB (DNA polymerase IV), members of the UmuC/DinB superfamily

To understand the mechanisms underlying mutagenesis in eukaryotes better, we have cloned mouse and human homologs of the Escherichia coli dinB gene. E. coli dinB encodes DNA polymerase IV and greatly increases spontaneous mutations when overexpressed. The mouse and human DinB1 amino acid sequences s...

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Argitaratua izan da:	Proc Natl Acad Sci U S A
Egile Nagusiak:	Gerlach, Valerie L., Aravind, L., Gotway, Garrett, Schultz, Roger A., Koonin, Eugene V., Friedberg, Errol C.
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	National Academy of Sciences 1999
Gaiak:	Biological Sciences
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18388/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10518552/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.21.11922
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