Human and mouse homologs of Escherichia coli DinB (DNA polymerase IV), members of the UmuC/DinB superfamily

To understand the mechanisms underlying mutagenesis in eukaryotes better, we have cloned mouse and human homologs of the Escherichia coli dinB gene. E. coli dinB encodes DNA polymerase IV and greatly increases spontaneous mutations when overexpressed. The mouse and human DinB1 amino acid sequences s...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Gerlach, Valerie L., Aravind, L., Gotway, Garrett, Schultz, Roger A., Koonin, Eugene V., Friedberg, Errol C.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18388/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10518552/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.21.11922
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!