Human and mouse homologs of Escherichia coli DinB (DNA polymerase IV), members of the UmuC/DinB superfamily

To understand the mechanisms underlying mutagenesis in eukaryotes better, we have cloned mouse and human homologs of the Escherichia coli dinB gene. E. coli dinB encodes DNA polymerase IV and greatly increases spontaneous mutations when overexpressed. The mouse and human DinB1 amino acid sequences s...

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Bibliografski detalji

Izdano u:	Proc Natl Acad Sci U S A
Glavni autori:	Gerlach, Valerie L., Aravind, L., Gotway, Garrett, Schultz, Roger A., Koonin, Eugene V., Friedberg, Errol C.
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 1999
Teme:	Biological Sciences
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18388/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10518552/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.21.11922
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