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Bioluminescence imaging of Smad signaling in living mice shows correlation with excitotoxic neurodegeneration
The TGF-β signaling pathway is a key organizer of injury and immune responses, and recent studies suggest it fulfills critical roles in CNS function and maintenance. TGF-β receptor activation results in phosphorylation of Smad proteins, which subsequently translocate to the nucleus to regulate gene...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1838750/ https://ncbi.nlm.nih.gov/pubmed/17110447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605077103 |
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