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Bioluminescence imaging of Smad signaling in living mice shows correlation with excitotoxic neurodegeneration

The TGF-β signaling pathway is a key organizer of injury and immune responses, and recent studies suggest it fulfills critical roles in CNS function and maintenance. TGF-β receptor activation results in phosphorylation of Smad proteins, which subsequently translocate to the nucleus to regulate gene...

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Detalhes bibliográficos
Main Authors: Luo, Jian, Lin, Amy H., Masliah, Eliezer, Wyss-Coray, Tony
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838750/
https://ncbi.nlm.nih.gov/pubmed/17110447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605077103
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