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Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice

Abnormal accumulation of β-amyloid (Aβ) in Alzheimer's disease (AD) is associated with prominent brain inflammation. Whereas earlier studies concluded that this inflammation is detrimental, more recent animal data suggest that at least some inflammatory processes may be beneficial and promote A...

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Hlavní autoři: Wyss-Coray, Tony, Yan, Fengrong, Lin, Amy Hsiu-Ti, Lambris, John D., Alexander, Jessy J., Quigg, Richard J., Masliah, Eliezer
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC125059/
https://ncbi.nlm.nih.gov/pubmed/12119423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162350199
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