Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice

Abnormal accumulation of β-amyloid (Aβ) in Alzheimer's disease (AD) is associated with prominent brain inflammation. Whereas earlier studies concluded that this inflammation is detrimental, more recent animal data suggest that at least some inflammatory processes may be beneficial and promote Aβ cle...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Wyss-Coray, Tony, Yan, Fengrong, Lin, Amy Hsiu-Ti, Lambris, John D., Alexander, Jessy J., Quigg, Richard J., Masliah, Eliezer
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2002
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125059/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12119423/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.162350199
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