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Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice

Abnormal accumulation of β-amyloid (Aβ) in Alzheimer's disease (AD) is associated with prominent brain inflammation. Whereas earlier studies concluded that this inflammation is detrimental, more recent animal data suggest that at least some inflammatory processes may be beneficial and promote Aβ cle...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Wyss-Coray, Tony, Yan, Fengrong, Lin, Amy Hsiu-Ti, Lambris, John D., Alexander, Jessy J., Quigg, Richard J., Masliah, Eliezer
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2002
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125059/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12119423/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.162350199
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