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Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice

Abnormal accumulation of β-amyloid (Aβ) in Alzheimer's disease (AD) is associated with prominent brain inflammation. Whereas earlier studies concluded that this inflammation is detrimental, more recent animal data suggest that at least some inflammatory processes may be beneficial and promote Aβ cle...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Principais autores: Wyss-Coray, Tony, Yan, Fengrong, Lin, Amy Hsiu-Ti, Lambris, John D., Alexander, Jessy J., Quigg, Richard J., Masliah, Eliezer
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2002
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125059/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12119423/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.162350199
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