High-throughput synergy screening identifies microbial metabolites as combination agents for the treatment of fungal infections

The high mortality rate of immunocompromised patients with fungal infections and the limited availability of highly efficacious and safe agents demand the development of new antifungal therapeutics. To rapidly discover such agents, we developed a high-throughput synergy screening (HTSS) strategy for...

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Main Authors: Zhang, Lixin, Yan, Kezhi, Zhang, Yu, Huang, Ren, Bian, Jiang, Zheng, Chuansen, Sun, Haixiang, Chen, Zhihui, Sun, Nuo, An, Rong, Min, Fangui, Zhao, Weibo, Zhuo, Ying, You, Jianlan, Song, Yongjie, Yu, Zhenyan, Liu, Zhiheng, Yang, Keqian, Gao, Hong, Dai, Huanqin, Zhang, Xiaoli, Wang, Jian, Fu, Chengzhang, Pei, Gang, Liu, Jintao, Zhang, Si, Goodfellow, Michael, Jiang, Yuanying, Kuai, Jun, Zhou, Guochun, Chen, Xiaoping
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2007
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838648/
https://ncbi.nlm.nih.gov/pubmed/17360571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609370104
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