High-throughput synergy screening identifies microbial metabolites as combination agents for the treatment of fungal infections

The high mortality rate of immunocompromised patients with fungal infections and the limited availability of highly efficacious and safe agents demand the development of new antifungal therapeutics. To rapidly discover such agents, we developed a high-throughput synergy screening (HTSS) strategy for...

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Detalhes bibliográficos
Main Authors: Zhang, Lixin, Yan, Kezhi, Zhang, Yu, Huang, Ren, Bian, Jiang, Zheng, Chuansen, Sun, Haixiang, Chen, Zhihui, Sun, Nuo, An, Rong, Min, Fangui, Zhao, Weibo, Zhuo, Ying, You, Jianlan, Song, Yongjie, Yu, Zhenyan, Liu, Zhiheng, Yang, Keqian, Gao, Hong, Dai, Huanqin, Zhang, Xiaoli, Wang, Jian, Fu, Chengzhang, Pei, Gang, Liu, Jintao, Zhang, Si, Goodfellow, Michael, Jiang, Yuanying, Kuai, Jun, Zhou, Guochun, Chen, Xiaoping
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838648/
https://ncbi.nlm.nih.gov/pubmed/17360571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609370104
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