High-throughput synergy screening identifies microbial metabolites as combination agents for the treatment of fungal infections

The high mortality rate of immunocompromised patients with fungal infections and the limited availability of highly efficacious and safe agents demand the development of new antifungal therapeutics. To rapidly discover such agents, we developed a high-throughput synergy screening (HTSS) strategy for...

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Bibliografiset tiedot
Päätekijät: Zhang, Lixin, Yan, Kezhi, Zhang, Yu, Huang, Ren, Bian, Jiang, Zheng, Chuansen, Sun, Haixiang, Chen, Zhihui, Sun, Nuo, An, Rong, Min, Fangui, Zhao, Weibo, Zhuo, Ying, You, Jianlan, Song, Yongjie, Yu, Zhenyan, Liu, Zhiheng, Yang, Keqian, Gao, Hong, Dai, Huanqin, Zhang, Xiaoli, Wang, Jian, Fu, Chengzhang, Pei, Gang, Liu, Jintao, Zhang, Si, Goodfellow, Michael, Jiang, Yuanying, Kuai, Jun, Zhou, Guochun, Chen, Xiaoping
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2007
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838648/
https://ncbi.nlm.nih.gov/pubmed/17360571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609370104
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