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Reduction of experimental gentamicin nephrotoxicity in rats by dietary calcium loading.

Since gentamicin accumulates in the renal cortex before renal failure and calcium reduces gentamicin binding to cell membranes, we examined the effect of dietary calcium loading on gentamicin toxicity in male F344 rats. Rats were fed either a normal (0.5%)- or a high (4%)-calcium-content chow. Calci...

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Detalhes bibliográficos
Main Authors: Bennett, W M, Elliott, W C, Houghton, D C, Gilbert, D N, DeFehr, J, McCarron, D A
Formato: Artigo
Idioma:Inglês
Publicado em: 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC183773/
https://ncbi.nlm.nih.gov/pubmed/7137986
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