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Reduction of experimental gentamicin nephrotoxicity in rats by dietary calcium loading.

Since gentamicin accumulates in the renal cortex before renal failure and calcium reduces gentamicin binding to cell membranes, we examined the effect of dietary calcium loading on gentamicin toxicity in male F344 rats. Rats were fed either a normal (0.5%)- or a high (4%)-calcium-content chow. Calci...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Bennett, W M, Elliott, W C, Houghton, D C, Gilbert, D N, DeFehr, J, McCarron, D A
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1982
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC183773/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7137986/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.22.3.508
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