Reduction of experimental gentamicin nephrotoxicity in rats by dietary calcium loading.

Since gentamicin accumulates in the renal cortex before renal failure and calcium reduces gentamicin binding to cell membranes, we examined the effect of dietary calcium loading on gentamicin toxicity in male F344 rats. Rats were fed either a normal (0.5%)- or a high (4%)-calcium-content chow. Calci...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Bennett, W M, Elliott, W C, Houghton, D C, Gilbert, D N, DeFehr, J, McCarron, D A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1982
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC183773/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7137986/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.22.3.508
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