Double duplex invasion by peptide nucleic acid: A general principle for sequence-specific targeting of double-stranded DNA
Pseudocomplementary PNAs containing diaminopurine⋅thiouracil base pairs have been prepared and are shown to bind with high specificity and efficiency to complementary targets in double-stranded DNA by a mechanism termed “double duplex invasion” in which the duplex is unwound and both DNA strands are...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Proc Natl Acad Sci U S A |
|---|---|
| Prif Awduron: | , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
National Academy of Sciences
1999
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18367/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10518531/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.21.11804 |
| Tagiau: |
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
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