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Double duplex invasion by peptide nucleic acid: A general principle for sequence-specific targeting of double-stranded DNA

Pseudocomplementary PNAs containing diaminopurine⋅thiouracil base pairs have been prepared and are shown to bind with high specificity and efficiency to complementary targets in double-stranded DNA by a mechanism termed “double duplex invasion” in which the duplex is unwound and both DNA strands are...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Lohse, Jesper, Dahl, Otto, Nielsen, Peter E.
פורמט: Artigo
שפה:Inglês
יצא לאור: The National Academy of Sciences 1999
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC18367/
https://ncbi.nlm.nih.gov/pubmed/10518531
תגים: הוספת תג
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