Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes

Little is known about the higher-order structure of prespliceosomal A complexes, in which pairing of the pre-mRNA's splice sites occurs. Here, human A complexes were isolated under physiological conditions by double-affinity selection. Purified complexes contained stoichiometric amounts of U1,...

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Detalhes bibliográficos
Main Authors: Behzadnia, Nastaran, Golas, Monika M, Hartmuth, Klaus, Sander, Bjoern, Kastner, Berthold, Deckert, Jochen, Dube, Prakash, Will, Cindy L, Urlaub, Henning, Stark, Holger, Lührmann, Reinhard
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829389/
https://ncbi.nlm.nih.gov/pubmed/17332742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601631
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