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Protein composition of human prespliceosomes isolated by a tobramycin affinity-selection method

Detailed knowledge of the composition and structure of the spliceosome and its assembly intermediates is a prerequisite for understanding the complex process of pre-mRNA splicing. To this end, we have developed a tobramycin affinity-selection method that is generally applicable for the purification...

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Autors principals: Hartmuth, Klaus, Urlaub, Henning, Vornlocher, Hans-Peter, Will, Cindy L., Gentzel, Marc, Wilm, Matthias, Lührmann, Reinhard
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC139210/
https://ncbi.nlm.nih.gov/pubmed/12477934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.262483899
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