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Reversible Reduction of Nitroxides to Hydroxylamines: the Roles for Ascorbate and Glutathione

Biological applications of stable nitroxyl radicals, NR, include their use as contrast agents for magnetic resonance imaging, spin labels, superoxide dismutase mimics, and antioxidants. The rapid reduction of NR in biological samples into hydroxylamines, HA, significantly limits their application. I...

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Detaylı Bibliyografya
Asıl Yazarlar: Bobko, Andrey A., Kirilyuk, Igor A., Grigor'ev, Igor A., Zweier, Jay L., Khramtsov, Valery V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829321/
https://ncbi.nlm.nih.gov/pubmed/17210453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2006.11.007
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