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Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival

Coupled cellular respiration requires that ATP and ADP be efficiently exchanged between the cytosol and the mitochondrial matrix. When growth factors are withdrawn from dependent cells, metabolism is disrupted by a defect in ATP/ADP exchange across the mitochondrial membranes. Unexpectedly, we find...

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Main Authors: Vander Heiden, Matthew G., Chandel, Navdeep S., Li, Xiao Xian, Schumacker, Paul T., Colombini, Marco, Thompson, Craig B.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC18290/
https://ncbi.nlm.nih.gov/pubmed/10781072
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