Bcl-x(L) Prevents the Initial Decrease in Mitochondrial Membrane Potential and Subsequent Reactive Oxygen Species Production during Tumor Necrosis Factor Alpha-Induced Apoptosis

The Bcl-2 family of proteins are involved in regulating the redox state of cells. However, the mode of action of Bcl-2 proteins remains unclear. This work analyzed the effects of Bcl-x(L) on the cellular redox state after treatment with tumor necrosis factor alpha (TNF-α) or exogenous oxidants. We s...

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Hlavní autoři: Gottlieb, Eyal, Vander Heiden, Matthew G., Thompson, Craig B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2000
Témata:
Cell Growth and Development
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC86039/
https://ncbi.nlm.nih.gov/pubmed/10891504
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