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Mitochondrial Regulation of Cell Survival and Death During Low-Oxygen Conditions

Mitochondria can initiate cell death or activate genes that promote cell survival in response to low oxygen. The BCL-2 family of proteins regulate cell death in response to anoxia (0–0.5% O(2)). By contrast, under hypoxia (0.5–3% O(2)), mitochondrial oxidative stress activates hypoxia-inducible fact...

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Detalhes bibliográficos
Main Authors: Snyder, Colleen M., Chandel, Navdeep S.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821141/
https://ncbi.nlm.nih.gov/pubmed/19580395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2009.2730
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