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Nitric Oxide Induces Cell Death by Regulating Anti-Apoptotic BCL-2 Family Members
Nitric oxide (NO) activates the intrinsic apoptotic pathway to induce cell death. However, the mechanism by which this pathway is activated in cells exposed to NO is not known. Here we report that BAX and BAK are activated by NO and that cytochrome c is released from the mitochondria. Cells deficien...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2741604/ https://ncbi.nlm.nih.gov/pubmed/19768117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007059 |
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