Mouse Cyp4a isoforms: enzymatic properties, gender- and strain-specific expression, and role in renal 20-hydroxyeicosatetraenoic acid formation

AA (arachidonic acid) hydroxylation to 20-HETE (20-hydroxyeicosatetraenoic acid) influences renal vascular and tubular function. To identify the CYP (cytochrome P450) isoforms catalysing this reaction in the mouse kidney, we analysed the substrate specificity of Cyp4a10, 4a12a, 4a12b and 4a14 and de...

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Autori principali: Muller, Dominik N., Schmidt, Cosima, Barbosa-Sicard, Eduardo, Wellner, Maren, Gross, Volkmar, Hercule, Hantz, Markovic, Marija, Honeck, Horst, Luft, Friedrich C., Schunck, Wolf-Hagen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2007
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828894/
https://ncbi.nlm.nih.gov/pubmed/17112342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061328
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