Mouse Cyp4a isoforms: enzymatic properties, gender- and strain-specific expression, and role in renal 20-hydroxyeicosatetraenoic acid formation

AA (arachidonic acid) hydroxylation to 20-HETE (20-hydroxyeicosatetraenoic acid) influences renal vascular and tubular function. To identify the CYP (cytochrome P450) isoforms catalysing this reaction in the mouse kidney, we analysed the substrate specificity of Cyp4a10, 4a12a, 4a12b and 4a14 and de...

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Bibliografski detalji
Glavni autori: Muller, Dominik N., Schmidt, Cosima, Barbosa-Sicard, Eduardo, Wellner, Maren, Gross, Volkmar, Hercule, Hantz, Markovic, Marija, Honeck, Horst, Luft, Friedrich C., Schunck, Wolf-Hagen
Format: Artigo
Jezik:Inglês
Izdano: Portland Press Ltd. 2007
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828894/
https://ncbi.nlm.nih.gov/pubmed/17112342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061328
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