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Optimized Synthesis of Hydrogen-Bond Surrogate Helices: Surprising Effects of Microwave Heating on the Activity of Grubbs Catalysts

This manuscript discusses microwave-assisted solid-phase synthesis of hydrogen-bond surrogate based α-helices and analogues by ring-closing metathesis (RCM). Microwave-mediated RCM allows access to a greater variety of amino acid residues in the macrocycles in shorter reaction times and higher yield...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Chapman, Ross N., Arora, Paramjit S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2006
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828874/
https://ncbi.nlm.nih.gov/pubmed/17134282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol062443z
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