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Optimized Synthesis of Hydrogen-Bond Surrogate Helices: Surprising Effects of Microwave Heating on the Activity of Grubbs Catalysts
This manuscript discusses microwave-assisted solid-phase synthesis of hydrogen-bond surrogate based α-helices and analogues by ring-closing metathesis (RCM). Microwave-mediated RCM allows access to a greater variety of amino acid residues in the macrocycles in shorter reaction times and higher yield...
שמור ב:
| Main Authors: | , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2006
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1828874/ https://ncbi.nlm.nih.gov/pubmed/17134282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol062443z |
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