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Evaluation of Biologically Relevant Short α-Helices Stabilized by a Main-Chain Hydrogen-Bond Surrogate

We previously reported the design and synthesis of a new class of artificial α-helices in which an N-terminal main-chain hydrogen bond is replaced by a carbon–carbon bond derived from a ring-closing metathesis reaction [Chapman, R. N.; Dimartino, G.; Arora, P. S. J. Am. Chem. Soc.2004, 126, 12252–12...

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Main Authors: Wang, Deyun, Chen, Kang, Kulp, John L., Arora, Paramjit S.
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828873/
https://ncbi.nlm.nih.gov/pubmed/16834399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja062710w
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