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Evaluation of Biologically Relevant Short α-Helices Stabilized by a Main-Chain Hydrogen-Bond Surrogate
We previously reported the design and synthesis of a new class of artificial α-helices in which an N-terminal main-chain hydrogen bond is replaced by a carbon–carbon bond derived from a ring-closing metathesis reaction [Chapman, R. N.; Dimartino, G.; Arora, P. S. J. Am. Chem. Soc.2004, 126, 12252–12...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1828873/ https://ncbi.nlm.nih.gov/pubmed/16834399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja062710w |
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