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Sonic hedgehog acts at multiple stages during pancreatic tumorigenesis
Activation of sonic hedgehog (Shh) signaling occurs in the majority of pancreatic ductal adenocarcinomas. Here we investigate the mechanisms by which Shh contributes to pancreatic tumorigenesis. We find that Shh expression enhances proliferation of pancreatic duct epithelial cells, potentially throu...
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| Glavni autori: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2007
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1828712/ https://ncbi.nlm.nih.gov/pubmed/17372229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701158104 |
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