A critical role for the E3-ligase activity of c-Cbl in VEGFR-2-mediated PLCγ1 activation and angiogenesis

Activation of phospholipase Cγ1 (PLCγ1) by vascular endothelial growth factor receptor-2 (VEGFR-2) in endothelial cells in part is responsible for angiogenesis in vivo. The cellular mechanisms exerting negative control over PLCγ1 activation, however, remain unaddressed. Here by using in vitro and in...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Singh, Amrik J., Meyer, Rosana D., Navruzbekov, Gyulmagomed, Shelke, Rajani, Duan, Lei, Band, Hamid, Leeman, Susan E., Rahimi, Nader
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828708/
https://ncbi.nlm.nih.gov/pubmed/17372230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700809104
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars