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Serial Killing of Tumor Cells by Human Natural Killer Cells – Enhancement by Therapeutic Antibodies

BACKGROUND: Natural killer cells are an important component of the innate immune system. Anti-cancer therapies utilizing monoclonal antibodies also rely on the cytotoxicity of NK cells for their effectiveness. Here, we study the dynamics of NK cell cytotoxicity. METHODOLOGY/PRINCIPAL FINDINGS: We ob...

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Detalhes bibliográficos
Main Authors: Bhat, Rauf, Watzl, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828617/
https://ncbi.nlm.nih.gov/pubmed/17389917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000326
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