Phase II study of Cloretazine for the treatment of adults with recurrent glioblastoma multiforme

Cloretazine (VNP40101M) is a newly synthesized alkylating agent belonging to a novel class of alkylating agents called 1,2-bis(sulfonyl)hydrazines. Agents that belong to this class do not produce vinylating and chloroethylating species, and hence this class of alkylating agents is thought to have mi...

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Autori principali: Badruddoja, Michael A., Penne, Kara, Desjardins, Annick, Reardon, David A., Rich, Jeremy N., Quinn, Jennifer A., Sathornsumetee, Sith, Friedman, Allan H., Bigner, Darell D., Herndon, James E., Cahill, Ann, Friedman, Henry S., Vredenburgh, James J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Duke University Press 2007
Soggetti:
Clinical Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828104/
https://ncbi.nlm.nih.gov/pubmed/17108065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2006-022
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