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Adenovirus-mediated suppression of HMGI(Y) protein synthesis as potential therapy of human malignant neoplasias

High mobility group I (HMGI) proteins are overexpressed in several human malignant tumors. We previously demonstrated that inhibition of HMGI synthesis prevents thyroid cell transformation. Here, we report that an adenovirus carrying the HMGI(Y) gene in an antisense orientation (Ad-Yas) induced prog...

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主要な著者: Scala, Stefania, Portella, Giuseppe, Fedele, Monica, Chiappetta, Gennaro, Fusco, Alfredo
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences 2000
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC18219/
https://ncbi.nlm.nih.gov/pubmed/10759549
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