Onset of natural killer cell lymphomas in transgenic mice carrying a truncated HMGI-C gene by the chronic stimulation of the IL-2 and IL-15 pathway

Rearrangements of the high mobility group protein I-C (HMGI-C) gene, consisting in the loss of the carboxyl-terminal tail, have been frequently detected in benign human tumors of mesenchymal origin. We have previously demonstrated that transgenic (TG) mice carrying a truncated HMGI-C construct (HMGI...

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Detalhes bibliográficos
Main Authors: Baldassarre, Gustavo, Fedele, Monica, Battista, Sabrina, Vecchione, Andrea, Klein-Szanto, Andres J. P., Santoro, Massimo, Waldmann, Thomas A., Azimi, Nazli, Croce, Carlo M., Fusco, Alfredo
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC35452/
https://ncbi.nlm.nih.gov/pubmed/11427729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.141224998
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