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Adenovirus-mediated suppression of HMGI(Y) protein synthesis as potential therapy of human malignant neoplasias

High mobility group I (HMGI) proteins are overexpressed in several human malignant tumors. We previously demonstrated that inhibition of HMGI synthesis prevents thyroid cell transformation. Here, we report that an adenovirus carrying the HMGI(Y) gene in an antisense orientation (Ad-Yas) induced prog...

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Bibliografiset tiedot
Päätekijät: Scala, Stefania, Portella, Giuseppe, Fedele, Monica, Chiappetta, Gennaro, Fusco, Alfredo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The National Academy of Sciences 2000
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC18219/
https://ncbi.nlm.nih.gov/pubmed/10759549
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