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Decreased energetics in murine hearts bearing the R92Q mutation in cardiac troponin T
The thin filament protein cardiac troponin T (cTnT) is an important regulator of myofilament activation. Here we report a significant change in cardiac energetics in transgenic mice bearing the missense mutation R92Q within the tropomyosin-binding domain of cTnT, a mutation associated with a clinica...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC182182/ https://ncbi.nlm.nih.gov/pubmed/12952925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200315967 |
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