Loading...

Myosin-driven rescue of contractile reserve and energetics in mouse hearts bearing familial hypertrophic cardiomyopathy-associated mutant troponin T is mutation-specific

The thin filament protein troponin T (TnT) is a regulator of sarcomere function. Whole heart energetics and contractile reserve are compromised in transgenic mice bearing missense mutations at R92 within the tropomyosin-binding domain of cTnT, despite being distal to the ATP hydrolysis domain of myo...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: He, Huamei, Hoyer, Kirsten, Tao, Hai, Rice, Ronald, Jimenez, Jesus, Tardiff, Jil C, Ingwall, Joanne S
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515825/
https://ncbi.nlm.nih.gov/pubmed/22907055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.234252
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!