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Immunotherapeutic activity of a conjugate of a Toll-like receptor 7 ligand
The immunotherapeutic activity of Toll-like receptor (TLR) activators has been difficult to exploit because of side effects related to the release and systemic dispersion of proinflammatory cytokines. To overcome this barrier, we have synthesized a versatile TLR7 agonist, 4-[6-amino-8-hydroxy-2-(2-m...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1820696/ https://ncbi.nlm.nih.gov/pubmed/17360465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611624104 |
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