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Mechanism for inactivation of the mitotic inhibitory kinase Wee1 at M phase

Wee1, the inhibitory kinase of cyclin B/Cdc2, undergoes a phosphorylation-dependent catalytic inactivation at M phase of the mitotic cell cycle, but the precise mechanism for this inactivation is not known. Using Xenopus egg and extract systems, we show here that the kinase activity of Xenopus somat...

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Bibliografiske detaljer
Main Authors: Okamoto, Kengo, Sagata, Noriyuki
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820656/
https://ncbi.nlm.nih.gov/pubmed/17360425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607357104
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