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Mechanism for inactivation of the mitotic inhibitory kinase Wee1 at M phase

Wee1, the inhibitory kinase of cyclin B/Cdc2, undergoes a phosphorylation-dependent catalytic inactivation at M phase of the mitotic cell cycle, but the precise mechanism for this inactivation is not known. Using Xenopus egg and extract systems, we show here that the kinase activity of Xenopus somat...

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Autors principals: Okamoto, Kengo, Sagata, Noriyuki
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820656/
https://ncbi.nlm.nih.gov/pubmed/17360425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607357104
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