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A porphomethene inhibitor of uroporphyrinogen decarboxylase causes porphyria cutanea tarda

Porphyria cutanea tarda (PCT), the most common form of porphyria in humans, is due to reduced activity of uroporphyrinogen decarboxylase (URO-D) in the liver. Previous studies have demonstrated that protein levels of URO-D do not change when catalytic activity is reduced, suggesting that an inhibito...

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Detalles Bibliográficos
Main Authors: Phillips, John D., Bergonia, Hector A., Reilly, Christopher A., Franklin, Michael R., Kushner, James P.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820519/
https://ncbi.nlm.nih.gov/pubmed/17360334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700547104
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