The Hypoxia-Inducible Factor 2α N-Terminal and C-Terminal Transactivation Domains Cooperate To Promote Renal Tumorigenesis In Vivo

Hypoxia-inducible factor (HIF) is a heterodimeric transcription factor, consisting of an alpha subunit and a beta subunit, that controls cellular responses to hypoxia. HIFα contains two transcriptional activation domains called the N-terminal transactivation domain (NTAD) and the C-terminal transact...

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Bibliographic Details
Main Authors: Yan, Qin, Bartz, Steven, Mao, Mao, Li, Lianjie, Kaelin, William G.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2007
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820491/
https://ncbi.nlm.nih.gov/pubmed/17220275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01514-06
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