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Positive and Negative Regulation of Tetrahymena Telomerase Holoenzyme
Telomerase replenishes the telomeric repeats that cap eukaryotic chromosome ends. To perform DNA synthesis, the active site of telomerase reverse transcriptase (TERT) copies a template within the integral telomerase RNA (TER). In vivo, TERT and TER and additional subunits form a telomerase holoenzym...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1820490/ https://ncbi.nlm.nih.gov/pubmed/17220281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02105-06 |
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