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Positive and Negative Regulation of Tetrahymena Telomerase Holoenzyme

Telomerase replenishes the telomeric repeats that cap eukaryotic chromosome ends. To perform DNA synthesis, the active site of telomerase reverse transcriptase (TERT) copies a template within the integral telomerase RNA (TER). In vivo, TERT and TER and additional subunits form a telomerase holoenzym...

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Autori principali: Witkin, Keren L., Prathapam, Ramadevi, Collins, Kathleen
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820490/
https://ncbi.nlm.nih.gov/pubmed/17220281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02105-06
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